Download Chemistry and Molecular Aspects of Drug Design and Action by E. A. Rekka, P. N. Kourounakis PDF
By E. A. Rekka, P. N. Kourounakis
An ever-increasing call for for larger medicinal drugs, increased defense criteria, and monetary issues have all resulted in a dramatic paradigm shift within the manner that medicinal drugs are being found and constructed. referred to as rational drug layout, this modern procedure is outlined by way of 3 major steps: the invention of lead compounds, surgical manipulation to strengthen pharmacophores, and extra optimization to supply the simplest compounds.
Chemistry and Molecular elements of Drug layout and motion brings jointly a powerful number of world-renowned pharmacochemistry scientists who're presently defining the emergence of rational drug layout. providing perception from their very own really good learn, those pioneers spotlight the diversity of techniques being hired during this box, together with those who begin via contemplating both molecular mechanisms of drug motion, or the metabolizing enzyme motion happening within the constitution of a drug molecule. one other method they discover is one who starts off from the pathobiochemistry and pathophysiology of objective ailments. additionally, the ebook additionally considers drug improvement that uses already constructed compounds kept in info banks.
Divided into 5 elements, every one devoted to a number of features of the classical medicinal chemistry technique, the textual content makes it effortless for readers to target a box of particular interest.
- Chemical, Biochemical, and organic points of Pathophysiological Conditions
- Classical Medicinal Chemistry
- Drug layout, Chemical and Molecular facets of Drug Action
- Drug Xenobiotic Metabolism
- actual natural and Theoretical Medicinal Chemistry
While each one part might be studied independently, the mixed fabric during this quantity presents the main complete evaluation to be had on rational drug layout. This paintings is a useful source either for these getting into the sphere, in addition to these researchers trying to construct on present development.
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